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European Journal of Case Reports in... 2019To review infections by
OBJECTIVE
To review infections by
MATERIALS AND METHODS
A 79-year-old male patient, with a chronic aortic valve biological prosthesis, presented to hospital because of fever. First examinations were normal. However, 72 hours later was isolated in blood cultures, and so meropenem was prescribed. Nevertheless, fever and bacteraemia were still present 7 days later.
RESULTS
The transoesophageal echocardiogram revealed an enlarged image suggesting a periprosthetic abscess, confirmed with a PET-CT scan. The patient was sent for cardiac surgery, and biopsy samples confirmed the presence of
CONCLUSION
There are very few cases of infection in humans. Ours is the first described case of endocarditis.
LEARNING POINTS
is commonly detected in poultry but very few cases have been described in humans since it was first isolated in 1994. Some type of immunosuppression is identified in 90% of patients. is frequently resistant to many antibiotics including β-lactams, macrolides, quinolones and cephalosporins. The diagnosis is often difficult using conventional phenotypic methods, so genotypic methods may be necessary for confirmation.Ours is the first described case of infection by with endocardial-vascular involvement. However, cases of endocarditis due to other Bordetella species such as have been documented.
PubMed: 30931262
DOI: 10.12890/2019_000994 -
Innate Immunity Aug 2014Endotoxin is recognized as one of the virulence factors of the Bordetella avium bird pathogen, and characterization of its structure and corresponding genomic features...
Endotoxin is recognized as one of the virulence factors of the Bordetella avium bird pathogen, and characterization of its structure and corresponding genomic features are important for an understanding of its role in pathogenicity and for an improved general knowledge of Bordetella spp virulence factors. The structure of the biologically active part of B. avium LPS, lipid A, is described and compared to those of another bird pathogen, opportunistic in humans, Bordetella hinzii, and to that of Bordetella trematum, a human pathogen. Sequence analyses showed that the three strains have homologues of acyl-chain modifying enzymes PagL, PagP and LpxO, of the 1-phosphatase LpxE, in addition to LgmA, LgmB and LgmC, which are required for the glucosamine modification. MALDI mass spectrometry identified a high amount of glucosamine substituting the phosphate groups of B. avium lipid A; this modification was absent from B. hinzii and B. trematum. The acylation patterns of the three lipid As were similar, but they differed from those of Bordetella pertussis and Bordetella parapertussis. They were also found to be close to the lipid A structure of Bordetella bronchiseptica, a mammalian pathogen, only differing from the latter by the degree of hydroxylation of the branched fatty acid.
Topics: Amino Acid Sequence; Bordetella; Bordetella avium; Endotoxins; Fatty Acids; Genome, Bacterial; Glucosamine; Humans; Hydrolysis; Lipid A; Lipopolysaccharides; Molecular Sequence Data; Phosphates
PubMed: 24127384
DOI: 10.1177/1753425913506950 -
Annals of Laboratory Medicine Jul 2021
Review
Topics: Asia; Bordetella; Bordetella Infections; Humans; Pneumonia
PubMed: 33536366
DOI: 10.3343/alm.2021.41.4.439 -
Genome Announcements Oct 2013Bordetella hinzii colonizes the respiratory tracts of poultry but can also infect immunocompromised humans. Bordetella trematum, however, only infects humans, causing...
Bordetella hinzii colonizes the respiratory tracts of poultry but can also infect immunocompromised humans. Bordetella trematum, however, only infects humans, causing ear and wound infections. Here, we present the first draft genome sequences of strains B. hinzii ATCC 51730 and B. trematum CCUG 13902.
PubMed: 24158552
DOI: 10.1128/genomeA.00838-13 -
Emerging Infectious Diseases Nov 2021Patients with severe acute respiratory syndrome coronavirus 2 infection may have bacterial co-infections, including pneumonia and bacteremia. Bordetella hinzii...
Patients with severe acute respiratory syndrome coronavirus 2 infection may have bacterial co-infections, including pneumonia and bacteremia. Bordetella hinzii infections are rare, may be associated with exposure to poultry, and have been reported mostly among immunocompromised patients. We describe B. hinzii pneumonia and bacteremia in a severe acute respiratory syndrome coronavirus 2 patient.
Topics: Bacteremia; Bordetella; Bordetella Infections; COVID-19; Humans
PubMed: 34388087
DOI: 10.3201/eid2711.211468 -
Epidemiology and Infection Feb 2000Fifty-seven bacterial isolates previously identified as Bordetella avium or B. hinzii were characterized by restriction enzyme analysis (REA) and/or ribotyping. Twenty...
Fifty-seven bacterial isolates previously identified as Bordetella avium or B. hinzii were characterized by restriction enzyme analysis (REA) and/or ribotyping. Twenty restriction endonucleases were evaluated for REA. Digestion of chromosomal DNA from the 42 B. avium and 15 B. hinzii isolates with HinfI produced 8 and 7 distinct fingerprint profiles, respectively. Digestion with DdeI further discriminated these Bordetella species and produced 12 fingerprint profiles for B. avium and 4 profiles of B. hinzii. In addition, B. avium isolates were clearly distinguishable from B. hinzii isolates by ribotyping with the restriction endonuclease PvuII. The ribotype patterns of these two species of Bordetella were unique when compared to previously reported ribotype patterns for B. bronchiseptica isolates. Since it was possible to discern differences among isolates within each Bordetella species by REA analysis, we suggest that REA could be used in developing a typing system based on the fingerprint profiles generated.
Topics: Bacterial Typing Techniques; Bordetella; DNA Fingerprinting; DNA Restriction Enzymes; DNA, Bacterial; DNA, Ribosomal; Humans; Polymorphism, Restriction Fragment Length; Prohibitins; Restriction Mapping
PubMed: 10722134
DOI: 10.1017/s0950268899003337 -
New Microbes and New Infections Mar 2020We report a novel case of an infection with a pathogen usually detected in poultry, supporting a peripancreatic abscess formation as a complication of an acute...
We report a novel case of an infection with a pathogen usually detected in poultry, supporting a peripancreatic abscess formation as a complication of an acute necrotizing pancreatitis.
PubMed: 32025312
DOI: 10.1016/j.nmni.2020.100650 -
Emerging Infectious Diseases Nov 2021Although Bordetella hinzii coccobacilli is most commonly identified in respiratory tracts of birds and rodents, this organism has occasionally been isolated in human...
Although Bordetella hinzii coccobacilli is most commonly identified in respiratory tracts of birds and rodents, this organism has occasionally been isolated in human infections. We describe a case of B. hinzii spontaneous bacterial peritonitis in Missouri, USA. Whole-genome sequencing of blood and peritoneal fluid isolates confirmed B. hinzii infection.
Topics: Bordetella; Bordetella Infections; Humans; Missouri; Peritonitis
PubMed: 34463239
DOI: 10.3201/eid2711.211428 -
International Journal of Systematic and... Dec 2016Bordetella hinzii is known to cause respiratory disease in poultry and has been associated with a variety of infections in immunocompromised humans. In addition, there...
Bordetella hinzii is known to cause respiratory disease in poultry and has been associated with a variety of infections in immunocompromised humans. In addition, there are several reports of B. hinzii infections in laboratory-raised mice. Here we sequenced and analysed the complete genome sequences of multiple B. hinzii-like isolates, obtained from vendor-supplied C57BL/6 mice in animal research facilities on different continents, and we determined their taxonomic relationship to other Bordetella species. The whole-genome based and 16S rRNA gene based phylogenies each identified two separate clades in B. hinzii, one was composed of strains isolated from poultry, humans and a rabbit whereas the other clade was restricted to isolates from mice. Distinctly different estimated DNA-DNA hybridization values, average nucleotide identity scores, gene content, metabolic profiles and host specificity all provide compelling evidence for delineation of the two species, B. hinzii - from poultry, humans and rabbit - and Bordetella pseudohinzii sp. nov. type strain 8-296-03T (=NRRL B-59942T=NCTC 13808T) that infect mice.
Topics: Animals; Bacterial Typing Techniques; Base Composition; Bordetella; DNA, Bacterial; Fatty Acids; Humans; Mice; Mice, Inbred C57BL; Nucleic Acid Hybridization; Phylogeny; Poultry; RNA, Ribosomal, 16S; Rabbits; Sequence Analysis, DNA
PubMed: 27707434
DOI: 10.1099/ijsem.0.001540 -
The Journal of International Medical... Jan 2024An increasing number of reports have described the pathogenic nature of several non-classical spp. Among them, and have been implicated in a myriad of...
An increasing number of reports have described the pathogenic nature of several non-classical spp. Among them, and have been implicated in a myriad of respiratory-associated infections in humans and animals. We report the isolation of a genetically close relative of and from the sputum of a woman in her early 60s with extensive bronchiectasis who presented with fever and brown colored sputum. The isolate had initially been identified as by API 20NE, the identification system for non-enteric Gram-negative rod bacteria. Sequencing of the 16S rDNA, , , and genes used in the multilocus sequence typing scheme could not resolve the identity of this isolate. Whole-genome single nucleotide polymorphism analysis positioned the isolate between and in the phylogenetic tree, forming a distinct cluster. Whole-genome sequencing enabled the further identification of this rare organism, and should be considered for wider applications, especially the confirmation of organism identity in the clinical diagnostic microbiology laboratory.
Topics: Humans; Animals; Female; Bordetella Infections; Phylogeny; Bordetella; Bronchiectasis; Respiratory Tract Infections
PubMed: 38216150
DOI: 10.1177/03000605231214464